Chinese panel of aging biomarkers
Molecular and phenotypic aging biomarkers.
Why do we need aging biomarkers?
Aging is a time-dependent physiological functional decline that affects most living organisms. And this process is directly related to molecular changes. It is also the most important risk factor for many noncommunicable diseases. On the one hand, the identification of biomarkers of aging will contribute to the differentiation of people who have the same chronological age, but different versions of aging. Quantitative biomarkers of aging can also make a group of measurements for "healthy aging" and, in addition, predict life expectancy.
On the other hand, biomarkers of aging can also help researchers to narrow the scope of research to specific biological aspects in an attempt to explain the biological processes associated with aging and age-related diseases. Here we will examine phenotypic and molecular biomarkers of aging.
Phenotypic biomarkers can be non-invasive, panoramic and easily accessible, whereas molecular biomarkers can reflect some molecular mechanisms underlying the age status. This review mainly reviews the results obtained in studies with humans (and in some rare cases with laboratory animals (mice) and nematodes).
Molecular biomarkers of aging
Molecular and phenotypic biomarkers of aging Version 1. F1000Res. 2017; 6: 860.
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